Dr. Yajun Li
Associate Professor
Fujian Institute of Research on the Structure of Matter,
Chinese Academy of Sciences
155 Yangqiao Road West, Fuzhou, 350002, P.R.China
Email: liyajun@fjirsm.ac.cn
Education and Research Experience
9/2016-till now Associate Professor Fujian Institute of Research on the Structure of Matter
9/2015-8/2016 Postdoc.
9/2014-8/2015 Postdoc.
2/2011-7/2014 Joint Ph.D., Shanghai Institute of Organic Chemistry (SIOC)
Advisor: Prof. Dr. Yongming Wu
9/2009-7/2014 Ph.D., Huazhong University of Science and Technology
Advisor: Prof. Dr. Yuefa Gong
9/2005-7/2009 B.S., Huazhong University of Science and Technology
Advisor: Prof. Dr. Yuefa Gong
Research Interests
Fluorine chemistry and radical chemistry
Publications
35.Iron-Catalyzed Oxyalkylation of Terminal Alkynes with Alkyl Iodides. Weili Deng, Changqing Ye, Yajun Li, Daliang Li, and Hongli Bao* org. lett. 2019. DOI: 10.1021/acs.orglett.8b03689.
34.Iron-catalyzed Radical Acyl-azidation of Alkenes with Aldehydes Synthesis of Unsymmetrical？β-Azido Ketones. Liang Ge, Yajun Li, and Hongli Bao* org. lett. 2019. DOI: 10.1021/acs.orglett.8b03688.
33.Copper-Catalyzed Radical 1,4-Difunctionalization of 1,3-Enynes with Alkyl Diacyl Peroxides and N-Fluorobenzenesulfonimide. Xiaotao Zhu, Weili Deng, Mong-Feng Chiou, Changqing Ye, Wujun Jian, Yuehua Zeng, Yihang Jiao, Liang Ge, Yajun Li, Xinhao Zhang*, and Hongli Bao* J. Am. Chem. Soc. 2019. DOI: 10.1021/jacs.8b11499.
32.Iron-Catalyzed Carboazidation of Alkenes and Alkynes. Haigen Xiong, Nagarajan Ramkumar, Mong-Feng Chiou, Wujun Jian, Yajun Li, Ji-Hu Su, Xinhao Zhang, and Hongli Bao* Nat. Commun. 2019. (Accepted)
31.Copper(I)-Catalyzed Tandem Reaction: Synthesis of 1,4-Disubstituted 1,2,3-Triazoles from Alkyl Diacyl Peroxides, Azidotrimethylsilane, and Alkynes. Muhammad Israr, Changqing Ye, Munira Taj Muhammad, Yajun Li, Hongli Bao* Beilstein J. Org. Chem. 2018, 14, 2916.
30.Iron-Catalyzed Dehydrative Alkylation of Propargyl Alcohol with Alkyl Peroxides to Form Substituted 1,3-Enynes. Changqing Ye, Bo Qian, Yajun Li, Min Su, Daliang Li* and Hongli Bao* Org. Lett. 2018, 20, 3202.
29.Merging Visible-Light Photocatalysis and Transition-Metal Catalysis in Three-Component Alkyl-Fluorination of Olefins with a Fluoride Ion. Weili Deng, Weiwei Feng, Yajun Li* and Hongli Bao* Org. Lett. 2018, 20, 4245.
28.Iron-Catalyzed Vinylic C-H Alkylation with Alkyl Peroxides. Liang Ge, Wujun Jian, Huan Zhou, Shaowei Chen, Changqing Ye, Bo Qian, Yajun Li and Hongli Bao* Chem. Asian J. 2018, 13, 2522.
27.HOTf-Catalyzed Alkyl-Heck-Type Reaction. Huan Zhou, Liang Ge, Jinshuai Song, Wujun Jian, Yajun Li, Chunsen Li* and Hongli Bao* iScience 2018, 3, 255.
26.A Metal-Free Approach for Br？nsted Acid Promoted C–H Alkylation of Heteroarenes with Alkyl Peroxides Yuehua zeng, Bo Qian, Yajun Li and Hongli Bao* Synthesis 2018, 50, 3250.
25.Iron-Catalyzed Carboiodination of Alkynes. Weili Deng, Yajun Li, Yong-Gui Li* and Hongli Bao* Synthesis 2018, 50, 2974.
24.Metal-Free Intermolecular Aminochlorination of Unactivated Alkenes. Nengbo Zhu, Yajun Li and Hongli Bao* Org. Chem. Front. 2018, 5, 1303.
23.Iron(III)-Catalyzed Ortho-Preferred Radical Nucleophilic Alkylation of Electron-Deficient Arenes. Fei Yu, Ting Wang, Huan Zhou, Yajun Li, Xinhao Zhang*, and Hongli Bao* Org. Lett. 2017, 19, 6538.
22.Recent Progress on Radical Decarboxylative Alkylation for C(sp3)-C Bond Formation. Yajun Li, Liang Ge, Munira Taj Muhammad, Hongli Bao* Synthesis 2017, 49, 5263.
21.γ-Amino Butyric Acid(GABA) Synthesis Enabled by Copper-Catalyzed Carboamination of Alkenes. Nengbo Zhu, Ting Wang, Liang Ge, Yajun Li, Xinhao Zhang,* and Hongli Bao* Org. Lett. 2017, 19, 4718.
20.Copper-Catalyzed Decarboxylative Alkylation of Terminal Alkynes. Changqing Ye, Yajun Li, Hongli Bao* Adv. Synth. Catal. 2017, 359, 3720.
19.Alkyl-Esterification of Vinylarenes Enabled by Visible-Light Induced Decarboxylation, Liang Ge, Yajun Li, Hongli Bao* Chem. Eur. J. 2017, 23, 11767.
18.Iron-Catalyzed Radical Decarboxylative Oxyalkylation of Terminal Alkynes with Alkyl Peroxides, Xiaotao Zhu, Changqing Ye, Yajun Li, and Hongli Bao* Chem. Eur. J. 2017, 23, 10254.
17.Iron Catalyzed Oxidative Hydroarylation, Methylarylation, and Diarylation of Vinylarenes to Generate Unsymmetrical 1,1-Diarylalkanes. Babu, Kaki Raveendra, Chen, Shaowei, Li, Yajun, Bao, Hongli*. Chin. J. Org. Chem. 2017, 37, 1160.
Before Join in FJIRSM
16.Y. Li, F. Fleming, Direct Conversion of Nitriles into Alkene “Isonitriles”, Angew. Chem. Int. Ed. 2016, 55, 14770 –14773.
15.X. Wang, Y. Li, Y. Guo, Z. Zhu, Y. Wu, W. Chao, Direct isoperfluoropropylation of arenediazonium salts with hexafluoropropylene, Org. Chem. Front., 2016, 3, 304-308.
14.Y. Li, A. Chao, F. Fleming, Isonitrile alkylations: a rapid route to imidazo[1,5-a]pyridines, Chem. Commun., 2016, 52, 2111-2113.
13.Y. Li, X. Wang, Y. Guo, Z. Zhu, Y. Wu, Y. Gong, Direct heptafluoroisopropylation of arylboronic acids via hexafluoropropene (HFP), Chem. Commun., 2016, 52, 796-799.
12.L. Zhang, Y. Li, Y. Yuan, B. Zhang, Y. Gao, Y. Wu, L. Song, Synthesis of multisubstituted tetrahydroquinolines through aza-Michael/ Michael addition catalyzed by quaternary ammonium salt, Synlett, 2014, 25, 1781-1785.
11.L. Zhang, Y. Li, L. Zhang, Y. Wu, Vicinal bis(trifluoroacetimidoyl chloride)s: a novel building block for the synthesis of benzo-fused eight-membered rings via [2+2+2] cycloadditions, Org. Biomol. Chem., 2014, 12, 1040-1043.
10.Y. Li, L. Zhang, L. Zhang, Y. Wu, Y. Gong, Cu-catalyzed tandem reactions of fluorinated alkynes with sulfonyl azides en route to 2-trifluoromethylquinolines, Org. Biomol. Chem., 2013, 11, 7267-7270. Highlighted by Synfacts, 2014, 10, 13.
9.Y. Li, L. Zhang, L. Zhang, Y. Wu, Y. Gong, Rhodium-catalyzed intramolecular difluoromethylenative dearomatization of phenols, Eur. J. Org. Chem., 2013, 8039–8047.
8.Y. Li, J. Zhu, L. Zhang, Y. Wu, Y. Gong, Synthesis of fluorine-containing multisubstituted phenanthridines by rhodium-catalyzed alkyne [2+2+2] cycloaddition and tandem sp2 C-H difluoromethylenation, Chem. Eur. J., 2013, 19, 8294-8299.
7.S. Li, Z. Li, Y. Yuan, Y. Li, L. Zhang, Y. Wu, Gold(I)-catalyzed aminohalogenation of fluorinated N'-aryl-N-propargyl amidines for the synthesis of imidazole derivatives under mild conditions, Chem. Eur. J., 2013, 19, 1496-1501.
6.S. Li, Y. Yuan, Y. Li, Z. Li, L. Zhang, Y. Wu, Pd-catalyzed coupling reaction of fluorinated propargyl amidines with aryl iodides, Org. Biomol. Chem., 2013, 11, 41-43.
5.S. Li, Z. Li, Y. Yuan, D. Peng, Y. Li, L. Zhang, Y. Wu, Au(I)-catalyzed intramolecular hydroamination of the fluorinated N’-aryl-N-propargyl amidines: mild conditions for the synthesis of 2-fluoroalkyl imidazole derivatives, Org. Lett., 2012, 14, 1130-1133.
4.Y. Li, J. Zhu, H. Xie, S. Li, D. Peng, Z. Li, L. Y. Wu, Y. Gong, Rh-catalyzed intramolecular sp(2) C-H bond difluoromethylenation, Chem. Comm., 2012, 48, 3136-3138.
3.S. Li, Z. Li, D. Peng, Y. Li, J. Zhu, H. Xie, Y. Yuan, Z. Chen, Y. Wu, Au(I)-catalyzted synthesis of 5-bromodifluoromethyl pyrazoles from fluorinated alkynyl ketones and hydrazine, Chinese J. Chem., 2011, 29, 2695-2701.
2.D. Lu, Y. Zhou, Y. Li, S. Yan, Y. Gong, Copper(II)-catalyzed asymmetric henry reaction of o-alkynylbenzaldehydes followed by gold(I)-mediated cycloisomerization: an enantioselective route to chiral 1H-isochromenes and 1,3-dihydroisobenzofurans, J. Org. Chem., 2011, 76, 8869-8878.
1.D. Lu, Y. Li, S. Yan, Y. Gong, Organocatalytic asymmetric tandem michael addition-hemiacetalization: a route to chiral dihydrocoumarins, chromanes, and 4H-chromenes, J. Org. Chem., 2010, 756, 6900-6907.
