2025

81. CuH-Catalyzed Asymmetric Desymmetrization of Cyclobutenes via Stereodivergent Hydroamination. Xiang Lei,§ Peng Luo,§ Shouang Lan, Wennan Dong, Chao Xu, Jinggong Liu, Shuang Yang, Qi Zhang,* Xinqiang Fang* ChemistryEurope. Accepted.

80. Ru-catalyzed isomerization/(transfer) hydrogenation of allylic alcohols. Shuang Yang,* Xinqiang Fang* Synthesis 2025, 57, 2423−2433. (Invited by Prof. Martin Oestreich)

79. Catalytic Diastereoselective Synthesis of Bicyclo[3.2.1]octanediones. Liyuan Zhou,# Lili Zhao,# Caiyi Ren, Qinqin Cui, Shouang Lan, Chao Xu, Wennan Dong, Chunyun Jiang, Xiangwen Kong,* Benlong Luo,* Shuang Yang,* and Xinqiang Fang* Adv. Synth. Catal. 2025, 367, e202500324.

78. Copper-Catalyzed Cloke-Wilson Rearrangement for the Synthesis of Dihydrofurans Containing Tetrasubstituted Carbon Atoms. Qinqin Cui,§ Shouang Lan,§ Xiang Lei, Chao Xu, Chunyun Jiang, Lili Zhao, Liyuan Zhou, Jinggong Liu, Cheng-Zhi Gu,* Shuang Yang,* Xinqiang Fang* Org. Chem. Front. 2025, DOI: 10.1039/d5qo00401b.

77. Copper-Catalyzed Dienylation of Aldehydes Using Propargylic Carbonates. Xiang Lei,§ Peng Luo,§ Wennan Dong,* Caiyi Ren, Qinqin Cui, Jinggong Liu, Xiang-Wen Kong, Shuang Yang,* Xinqiang Fang* Org. Lett. 2025, 27, 5355−5360.

76. Copper-Catalyzed Unconventional Reactivities of Propargylic Esters. Shuang Yang,* Xinqiang Fang* Synlett 2024, 146, 33543−33560. (Invited by Prof. Debabrata Maiti)

75. Copper-Catalyzed Asymmetric Nucleophilic Opening of 1,1,2,2-Tetrasubstituted Donor-Acceptor Cyclopropanes for the Synthesis of α-Tertiary Amines. Shouang Lan,§ Qinqin Cui,§ Defu Luo, Siyu Shi, Chengyang He, Shengyu Huang, Chao Xu, Lili Zhao, Jinggong Liu,* Cheng-Zhi Gu,* Shuang Yang, Xinqiang Fang* J. Am. Chem. Soc. 2025, 147, 1172–1185.


2024


75. Copper-Catalyzed Asymmetric Nucleophilic Opening of 1,1,2,2-Tetrasubstituted Donor-Acceptor Cyclopropanes for the Synthesis of α-Tertiary Amines. Shouang Lan,§ Qinqin Cui,§ Defu Luo, Siyu Shi, Chengyang He, Shengyu Huang, Chao Xu, Lili Zhao, Jinggong Liu,* Cheng-Zhi Gu,* Shuang Yang, Xinqiang Fang* J. Am. Chem. Soc. DOI:10.1021/jacs.4c14944.

74. Ruthenium-Catalyzed Formal Asymmetric Reductive Isomerization of α-Hydroxyenones. Wennan Dong, Caiyi Ren, Lixuan Zhu, Peng Luo, Zhifei Zhao, Shouang Lan, Jinggong Liu Shuang Yang, Qi Zhang,* Xinqiang Fang* ACS Catal. 2024,14, 18753−18764.

Highlighted by:

https://mp.weixin.qq.com/s/WKiKqeF-TQ4Q5xHIm5RzTQ

https://mp.weixin.qq.com/s/7jCDOdBtHt1_sVTgpsUmPg

73. BMIDA-Directed Catalytic Asymmetric Transfer Hydrogenation for Enantioselective Access to α-Boryl Alcohols. Shuang Yang,Xinqiang Fang* Synlett DOI: 10.1055/a-2456-9333. (invited by Prof. Ruben Martin)

72. Catalytic Asymmetric Transfer Hydrogenation of β,γ-Unsaturated α-Diketones. Zhifei Zhao,§ Wennan Dong,§ Jinggong Liu,Shuang Yang,Andrej Emanuel Cotman,Qi Zhang,* Xinqiang Fang* J. Am. Chem. Soc. doi.org/10.1021/jacs.4c11070. 

Highlighted by:

https://mp.weixin.qq.com/s/-d5j148EKpLssMJ8gxgV1Q

https://mp.weixin.qq.com/s/xcklWSzqOaEpMprHHn9eoA

https://mp.weixin.qq.com/s/Hp5I8_wLOQtjQMRQ7SwtFQ

71. Copper-catalyzed yne-allylic substitutions: concept and recent developments. Shuang Yang,* Xinqiang Fang* Beilstein J. Org. Chem. 2024,20,2739–2775. (Invited by Prof. Jaesook Yun for the thematic issue"Copper catalysis: a constantly evolving field".)

70. Rapid Construction of Polycyclic Skeletons via Brønsted Base-Catalyzed Annulations of Ethylidene 1,3-Indenediones and Vinyl 1,2-Diketones. Lixuan Zhu,§ Haotian Luo,§ Jinggong Liu,* Benlong Luo,* Shuang Yang, Xinqiang Fang,* Org. Lett. 2024, 26, 5893–5898. (highlighted by ACS Publications: https://mp.weixin.qq.com/s/2OAoxqqD_rRsSdXdR_dpVg)


69. Regio- and Stereoselective Transfer Hydrogenation of Aryloxy Group-Substituted Unsymmetrical 1,2-Diketones: Synthetic Applications and Mechanistic Studies. Wenjun Liu,Caiyi Ren,Liyuan Zhou,Haotian Luo,Xiangjian Meng,Peng Luo,Yingkun Luo,Wennan Dong,Shouang Lan,Jinggong Liu,Shuang Yang,Qi Zhang,* Xinqiang Fang,* J. Am. Chem. Soc. 2024,146, 20092–20106.

Highlighted by:

https://mp.weixin.qq.com/s/RriGlQrp6hmlseV6S_evCw  

https://mp.weixin.qq.com/s/baXPYmS-NTMsu7-bhY_oDA

https://mp.weixin.qq.com/s/X7mAFk8ciDe43eREkUW0wg

https://mp.weixin.qq.com/s/AzkWp1wg8aBMoPULEOeQwA

68. Catalytic Asymmetric Transfer Hydrogenation of Acylboronates: BMIDA as the Privileged Directing Group. Xiangjian Meng,§ Shouang Lan,§ Ting Chen, Haotian Luo, Lixuan Zhu, Nanchu Chen, Jinggong Liu, Shuang Yang, Andrej Emanuel Cotman, Qi Zhang,* Xinqiang Fang,* J. Am. Chem. Soc. 2024, 146, 20357–20369. (highlight:

https://www.cas.cn/syky/202406/t20240617_5021492.shtml?from=singlemessage

https://mp.weixin.qq.com/s/_3IWNx0lAZS-s27kZm-T7A

https://mp.weixin.qq.com/s/mLS0UiPLU5ZUl6MaGCZb8Q  

https://mp.weixin.qq.com/s/-E5wQOM24CAu8fqapA2wxA

https://mp.weixin.qq.com/s/yj5pyeLu3NKqzBjbpaYMFg)

67. Copper-catalyzed amine-mediated ynepropargylic substitution. Chunyun Jiang,§ Defu Luo,§ Xiangjian Meng,Qinqin Cui,Lili Zhao,Jinggong Liu,* Shuang Yang,Xinqiang Fang,* Org. Chem. Front. 2024,11,3946–3951.

66. Asymmetric Transfer Hydrogenation of Cyclobutenediones. Shouang Lan,§ Huangjiang Huang,§ Wenjun Liu,Chao Xu,Xiang Lei,Wennan Dong,Jinggong Liu,Shuang Yang,Andrej Emanuel Cotman,Qi Zhang,* and Xinqiang Fang,* J. Am. Chem. Soc. 2024,146, 4942-4957. (highlight: https://mp.weixin.qq.com/s/Cf-XheAGlA7KiIJqVy1xkw https://mp.weixin.qq.com/s/UVYmmtE2eJSd9EJFNAJ5bQ)


 

65. Copper-catalyzed Asymmetric Yne-allylic Substitution Using Electron-rich Arenes. Defu Luo§, Shengtong Niu§, Fan Gong,Chao Xu,Shouang Lan,Jinggong Liu*,Shuang Yang,Xinqiang Fang*, ACS Catal. 2024, 14, 2746–2757. (highlight: https://mp.weixin.qq.com/s/H-hNhsCvyTene8XnaydC0w ) 

64. Transition-metal and base-free ether synthesis via alcohol-participated yne-allylic substitution. Chao Xu§,Yingkun Luo§,Shengtong Niu*,Fan Gong,Shouang Lan,Benlong Luo*,Jinggong Liu*,Shuang Yang,Xinqiang Fang*,Green Synth. Catal. 2024,5, 303–309. 

63. Kinetic Resolutions Enabled by N-Heterocyclic Carbene Catalysis: An Update. Shuang Yang*,Xinqiang Fang*, Chin. J. Org. Chem. 2024, 44, 448–480. (invited paper; highlight: https://mp.weixin.qq.com/s/2-naJkaIO2hVaChHlqHgOw) 

 

2023

62. Carboxyl group assisted isodesmic meta-C–H iodination of phenethylamines, benzylamines, and 2-aryl anilines. Lei Yang, Lei Yang, Xinchao Wang, Meng Zhang, Shangda Li, Xinqiang Fang*, Gang Li *, Org. Chem. Front. 2023, 10, 3760–3765 

61. Copper-catalyzed Umpolung Reactivity of Propargylic Carbonates in the Presence of Diboronates: One Stone Four Birds. Wennan Dong, Zhifei Zhao, Cheng-Zhi Gu*, Jing-Gong Liu, Shuang Yang, Xinqiang Fang*, J. Am. Chem. Soc. 2023, 145, 27539–27554.  (highlight: https://mp.weixin.qq.com/s/hcabOgFBvztlHahP0b9kKg; https://mp.weixin.qq.com/s/AL1_iRMQbqpyoNJMz_bGVQ; https://mp.weixin.qq.com/s/J0PBtYRs9AnjwtgH-hk4Hg; https://mp.weixin.qq.com/s/rVHj1SoyR37F7ouZzgo_ig)  

60. Asymmetric Hydrogenation and Transfer Hydrogenation of Diketones. Shuang Yang, Xinqiang Fang*, Tetrahedron 2023, 145, 133609. (invited paper)

59. Copper-Catalysed Rearrangement of Cyclic Ethynylethylene Carbonates: Synthetic Applications and Mechanistic Studies, Chao Xu,§ Hao Zhang,§ Shouang Lan, Jinggong Liu, Shuang Yang, Qi Zhang,* Xinqiang Fang*, Angew. Chem. Int. Ed. 2023, e292219064.  (highlight: https://mp.weixin.qq.com/s/hDLBalci4n-LIpm3jx0nhg; https://mp.weixin.qq.com/s/h1E-HKf6K0t-FrQjlG_qEA )   

 


58. Dynamic Kinetic Resolution of β-Substituted α-Diketones via Asymmetric Transfer Hydrogenation, Ting Chen,§ Wenjun Liu,§ Wei Gu, Shengtong Niu, Shouang Lan, Zhifei Zhao, Fan Gong, Jinggong Liu, Shuang Yang, Andrej Emanuel Cotman, Jinshuai Song,* Xinqiang Fang*, J. Am. Chem. Soc. 2023, 145, 585–599.  (highlight: https://mp.weixin.qq.com/s/aHyHQVVBAbssTksRPxqnzA) 

57. Catalytic Synthesis of Seven-Membered Carbocycles via Ring Expansion of Cyclic β-Ketoesters, Li Chen,§  Huangjiang Huang,§  Benlong Luo,* Jinggong Liu,* Shuang Yang,* and Xinqiang Fang*, New J. Chem. 2023, 47, 41–45. 

 

2022

56. Oxa-Nazarov Cyclization-Michael Addition Sequence for the Rapid Construction of Dihydrofuranones, Ting Chen,§ Fan Gong,§ Sakkani Nagaraju,* Jinggong Liu,* Shuang Yang, Xingkuan Chen,* and Xinqiang Fang*, Org. Lett. 2022, 24, 8837–8842. 

55. Asymmetric Semipinacol Rearrangement Enabled by Copper-Catalyzed Propargylic Alkylation, Fan Gong,§ Xiangjian Meng,§ Shouang Lan, Jinggong Liu, Shuang Yang, Xinqiang Fang,* ACS Catal. 2022, 12, 12036–12044. (highlight: https://mp.weixin.qq.com/s/Oq-as5B3ueIxYAb37YUnTg) 

 

54. Copper-Catalyzed Yne-Allylic Substitutions Using Stabilized Nucleophiles, Shengtong Niu, Yingkun Luo, Chao Xu, Jinggong Liu, Shuang Yang, Xinqiang Fang,* ACS Catal. 2022,  12,  6840–6850. (highlighted by Mark Lautens in Synfacts 2022, 18, 0982; 　　 https://mp.weixin.qq.com/s/xDSQ3GxtCBOFZkLS-sVEPg) 

 

53. Organocatalyzed Trifunctionalization of Alkynyl 1,2-Diones for the Concise Synthesis of Acyloxy Allylidene Malonates and γ-Alkylidenebutenolides, Li Chen, Shengtong Niu, Shouang Lan, Wenjun Liu, Shuang Yang,* Xinqiang Fang,* Green Chem. 2022, 24, 3623–3628.

52. Access to Enantioenriched Molecules with Diverse Fluorinated Tetrasubstituted Stereocenters Using Hydroxy as Kinetic Resolution Auxiliary Group, Syeda Tazeen Zehra, Shouang Lan, Hao Zhang, Jinggong Liu,* Shuang Yang, and Xinqiang Fang,* Org. Chem. Front., 2022, 9, 1040–1047. 

 

51. Copper-Catalyzed Diversified Annulations Between α-Diketones and Alkynyl α-Diketones, Xiangwen Kong, Fang Yu, Shengtong Niu, Fan Gong, Shuang Yang, Jinggong Liu, Benlong Luo,* Xinqiang Fang,* Chin. Chem. Lett. 2022, 33, 2997–3002. 

 

2021

50. Access to Enantioenriched Compounds Bearing Challenging Tetrasubstituted Stereocenters via Kinetic Resolution of Auxiliary Adjacent Alcohols, Shengtong Niu, Hao Zhang, Weici Xu,* Prasanta Ray Bagdi, Guoxiang Zhang, Jinggong Liu, Shuang Yang, Xinqiang Fang,* Nature Commun. 2021, 12: 3735. (Highlighted by X-MOL https://www.x-mol.com/news/682869; https://mp.weixin.qq.com/s/8L78K-IdRvv6wtJMxsNlGw; https://mp.weixin.qq.com/s/doahWnNEPNXzmNW4QU_vyA; https://mp.weixin.qq.com/s/Kx3wFlFc1HpoC_eH3Lddlw)

 

49.N-Heterocyclic Carbene-Catalyzed Asymmetric Synthesis of Cyclopentenones, Zhizhou Chen, Xiangwen Kong, ShengtongNiu, Shuang Yang,*Jinggong Liu, BenlongLuo, and Xinqiang Fang*,Org. Lett. 2021,  23, 3403–3408. 

(Featured in Org. Chem. Highlights: Organocatalyzed C-C Ring Construction: https://www.organic-chemistry.org/Highlights/2021/29November.shtm ).

　　  

48. Mechanistic Studies on N-Heterocyclic Carbene-Catalyzed Umpolung of β,γ-Unsaturated α-Diketones, Qi Zhang,Deb Kumar Das,Shuang Yang,Yao Fu,*Xinqiang Fang*,J. Org. Chem. 2021, 86, 4432–4439.  

47. Catalytic chemodivergent annulations between α-diketones and alkynyl α-diketones, Xiangwen Kong, Fang Yu,Zhizhou Chen, Fan Gong, Shuang Yang, Jinggong Liu,BenlongLuo, Xinqiang Fang*, Sci. China Chem. 2021,  64, 991–998. (Sci. China Chem. Top 20 Downloaded Articles in 2021)

46. Rapid Construction of Polycyclic Ketones and the Divergent Kinetic Resolution Using Ruthenium-Catalyzed Transfer Hydrogenation, ShouangLan,Hao Zhang, Zhizhou Chen, Shuang Yang,Xinqiang Fang*, Adv. Synth. Catal. 2021, 363, 2071–2077. 

45.Ti(OiPr)4-Facilitated Formal Deoxygenative Annulation of Alkynyl 1,2-Diketones for the Synthesis of Highly Functionalized Furans, ShouangLan,§Rui Liu,§Xiangwen Kong, Jinggong Liu, BenlongLuo, Shuang Yang,*and Xinqiang Fang*, Org. Lett. 2021, 23, 1504–1509.　　  

2020

44. Divergent Synthesis of Bicyclo[3.2.1]octenes and Cyclohexenes via Catalytic Annulations of Nazarov Reagent and Vinyl 1,2-Diketones, Wenjun Liu,ShengtongNiu, Zhifei Zhao, Shuang Yang,Jinggong Liu,*Yongjin Li,* and Xinqiang Fang*, Org. Lett. 2020, 22, 7572-7576. 


43. Lewis Acid-Catalyzed Asymmetric Alkynylation of Alkynyl 1,2-Diketones: Controllable Formation of 3(2H)-furanones and a-Hydroxy Ketones, Rui Liu, Shuang Yang, Zhizhou Chen, Xiangwen Kong, Houqiang Ding,* and Xinqiang Fang,* Org. Lett. 2020, 22, 6948-6953.


42. Asymmetric Catalytic Construction of Fully-Substituted Carbon Stereocenters Using Acyclic α-Branched β-Ketocarbonyls: The “Methyl Rule” Widely Exists, Deqian Sun,* Shuang Yang,* Xinqiang Fang,* Org. Chem. Front. 2020, 7, 3557-3577.


41. Catalytic Annulation of Alkynyl 1,2-Diketone Leading to Hydroxy Spirocyclopenteneindenedione: An Organic Dye with Strong Crystallization-Induced Emission and Data Storage Application, Zhizhou Chen, # Fang Yu, # Rui Liu, Xiangling Lin, Shuang Yang, Jinggong Liu,* Bolai Chen,* Sakkani Nagaraju, Min Zeng, Chenglin Ding, and Xinqiang Fang,* Org. Lett. 2020, 22, 2381？2385.

 

40. Organocatalyzed Kinetic Resolution of a-Functionalized Ketones: the Malonate Unit Leads the Way, Jian Liu,# Laxmaiah Vasamsetty,# Muhammad Anwar,# Shuang Yang,* Weici Xu,  Jinggong Liu, Sakkani Nagaraju, and Xinqiang Fang,* ACS Catal. 2020, 10, 2882-2893.

2019

39. Regioselectivity-Switchable Catalytic Annulations of Alkynyl α-Diketones and α-Cyanoketones, Sakkani Nagaraju,# Shuhua Liu,# Jinggong Liu,# Shuang Yang, Rui Liu, Zhizhou Chen, Banoth Paplal,and Xinqiang Fang,* Org. Lett. 2019, 21, 10075-10080. 

38. Stereodivergent Access to Enantioenriched Epoxy Alcohols with Three Stereogenic Centers via Ruthenium-Catalyzed Transfer Hydrogenation, Zhifei Zhao, Prasanta Ray Bagdi, Shuang Yang, Jinggong Liu, Weici Xu,* and Xinqiang Fang,* Org. Lett. 2019, 21, 5491-5494.

37. Asymmetric Synthesis of Dihydronaphthalene-1,4-diones via Carbene-Catalyzed Stereodivergent Reaction, Zhifei Zhao, Shuang Yang, Shouang Lan, Jinggong Liu, Shuhua Liu,* and Xinqiang Fang,* Adv. Synth. Catal. 2019, 361, 3943-3949.

36. Carbene-Catalyzed Asymmetric Friedel-Crafts Alkylation-Annulation Sequence and Rapid Synthesis of Indole-Fused Polycyclic Alkaloids, Muhammad Anwar, Shuang Yang, Weici Xu, Jinggong Liu, Saima Perveen, Xiangwen Kong, Syeda Tazeen Zehra, and Xinqiang Fang,* Communications Chemistry 2019, 2: 85. (The work was selected by Nature Press in the collection of celebrating Nobel Prize in Chemistry 2021 (total 23/35 research papers): https://www.nature.com/collections/fagcgjcbdf)

35. Bifunctional Thiourea-Catalyzed Asymmetric Inverse-Electron-Demand Diels-Alder Reaction of Allyl Ketones and Vinyl 1,2-Diketones via Dienolate Intermediate, Xinglong Li, Xiangwen Kong, Shuang Yang,* Miao Meng, Xinyue Zhan, Min Zeng, and Xinqiang Fang*, Org. Lett. 2019, 21, 1979-1983. (Highlighted by Organic Chemistry Portal, https://www.organic-chemistry.org/Highlights/2020/ 13January.shtm)

34. Kinetic Resolution of β-Ketoesters with Quaternary Stereocenters via Carbene-Catalyzed Benzoin Reaction, Syeda Tazeen Zehra,# Guoxiang Zhang,# Shuang Yang, and Xinqiang Fang,* Org. Biomol. Chem. 2019, 17, 2169–2173.   

33. Asymmetric Total Synthesis of Rotenoids via Organocatalyzed Dynamic Kinetic Resolution, Saima Perveen, Shuang Yang, Miao Meng, Weici Xu, Guoxiang Zhang, and Xinqiang Fang,* Communications Chemistry 2019, 2: 8 

32. Kinetic Resolution of 2,2-Disubstituted-1,3-Diketones via Carbene Catalysis, Weici Xu, Yuanzhen Li, Rui Liu, Shuang Yang, Jian Liu, and Xinqiang Fang,* Org. Chem. Front. 2019, 6, 290–298.  

　 

2018

31. Divergent Dynamic Kinetic Resolution of Racemic Mixture of Four Stereoisomers via N-Heterocyclic Carbene Organocatalysis, Laxmaiah Vasamsetty, Xiangwen Kong, Miao Meng, Shuang Yang, Weici Xu, Pogula Sreekanth Reddy, and Xinqiang Fang,* Chem. Asian J. 2018, 13, 3838–3844.  

30. Cyclopentadienone Formation from β,γ-Unsaturated Cyclopentenones and Its Application in Diels–Alder Reactions, Xiangwen Kong, Shuang Yang, Fang Yu, Laxmaiah Vasamsetty, Jian Liu, Shuhua Liu,*  Xiaozhi Liu,*  andXinqiang Fang,* J. Org. Chem. 2018, 83, 8953–8961.   

29. Bronsted Base-Catalyzed Annulation of Allyl Ketones and Alkynyl 1,2-Diketones, Xiangwen Kong, Jinshuai Song, Jian Liu, Miao Meng, Shuang Yang, Min Zeng, Xinyue Zhan, Chunsen Li,* and Xinqiang Fang,* Chem. Commun. 2018, 54, 4266–4269. (X. K. and J. S. equal contribution)  

28. N-Heterocyclic Carbene-Catalyzed Umpolung of β,γ-Unsaturated 1,2-Diketones, Jian Liu, Deb Kumar Das, Guoxiang Zhang, Shuang Yang, Hao Zhang, and Xinqiang Fang,* Org. Lett. 2018, 20, 64–67. (J. L. and D. D. equal contribution)

2017

27. Enantioselective intermolecular all-carbon [4+2] annulation via N-heterocyclic Carbene organocatalysis, Guoxiang Zhang, Weici Xu, Jian Liu, Deb Kumar Das, Shuang Yang, Saima Perveen, Hao Zhang, Xinglong Li and Xinqiang Fang,* Chem. Commun. 2017, 53, 13336-13339. (G.Z. and W.X. equal contribution) 

26. Book Chapter, Nonnitrogenous Organocatalysis, Andrew M. Harned, Ed. Chartper 7, Page 151-183, N-Heterocyclic Carbene Catalysis: Homoenolate and Enolate Reactivity, Xinqiang Fang,* and Yonggui Robin Chi,* CRC Press, Taylor & Francis Group, Dec-15, 2017. ISBN 9781498715034.

25. N-Heterocyclic Carbene-Catalyzed Umpolung of Alkynyl 1,2-Diketones, Xiangwen Kong, Guoxiang Zhang, Shuang Yang, Xiaozhi Liu, and Xinqiang Fang,* Adv. Synth. Catal. 2017, 359, 2729-2734.

24. Enantioselective Synthesis of 1,2-Dihydronaphthalenes via Oxidative N-Heterocyclic Carbene Catalysis, Saima Perveen, Zhifei Zhao, Guoxiang Zhang, Jian Liu, Muhammad Anwar, and Xinqiang Fang,* Org. Lett. 2017, 19, 2470-2473. 　　  

23. Kinetic Resolutions Enabled by N-Heterocyclic Carbene Catalysis, Shuang Yang, Xinqiang Fang,* Curr. Org. Syn. 2017, 14, 654. (invited review paper) 

　　  

22. A Genetically Encoded Allysine for the Synthesis of Proteins with Site-Specific Lysine Dimethylation, Zhipeng A. Wang, Yu Zeng, Yadagiri Kurra, Xin Wang, Jeffery M. Tharp, Erol C. Vatansever, Willie W. Hsu, Susie Dai, Xinqiang Fang,* and Wenshe R. Liu,* Angew. Chem., Int. Ed. 2017, 56, 212-216. 

2016

21. Stereodivergent Synthesis of Chromanones and Flavanones via Intramolecular Benzoin Reaction, Genfa Wen, Yingpeng Su, Guoxiang Zhang, Qiqiao Lin, Yujin Zhu, Qianqian Zhang, and Xinqiang Fang*, Org. Lett. 2016, 18, 3980-3983. 

20. Dynamic Kinetic Resolution Enabled by Intramolecular Benzoin Reaction: Synthetic Applications and Mechanistic Insights, Guoxiang Zhang, Shuang Yang, Xiaoyan Zhang, Qiqiao Lin, Deb K. Das, Jian Liu, and Xinqiang Fang*, J. Am. Chem. Soc. 2016, 138, 7932-7938. (Highlighted by Synfacts 2016, 972) 

19. N-Heterocyclic Carbene-catalyzed Desymmetrization of Functionalized 1,4-Dienes via Stetter Reaction, Qiqiao Lin, Yuanzhen Li, Deb Kumar Das, Guoxiang Zhang, Zhifei Zhao, Shuang Yang* and Xinqiang Fang*, Chem. Commun. 2016, 52, 6459-6462. 

18. Asymmetric Desymmetrization of 1,3-Diketones via Intramolecular Benzoin Reaction, Yuanzhen Li, Shuang Yang, Genfa Wen, Qiqiao Lin, Guoxiang Zhang, Lin Qiu, Xiaoyan Zhang, Guangfen Du,* Xinqiang Fang*. J. Org. Chem. 2016, 81, 2763-2769. 

17. Stereoselectivity of 6-Exo Cyclization of α-Carbamoyl Radicals, Song, L.; Fang, X.; Wang, Z.; Liu, K.; Li, C.* J. Org. Chem. 2016, 81, 2442-2450. 
Before 2016

16. Tuley, A.; Wang, Y.-S.; Fang, X.; Kurra, Y.; Rezenom, Y. H.; Liu, W. R.* The Genetic Incorporation of Thirteen Novel non-Canonical Amino Acids. Chem. Comm. 2014, 50, 2673-2675. 

15. Fang, X.#; Fu, Y.#; Long, M. C.; Haegele, J. A.; Ge, E. J.; Parvez, S.; Aye, Y.* Temporally Controlled Targeting of 4-Hydroxynonenal to Specific Proteins in Living Cells. J. Am. Chem. Soc. 2013, 135, 14496-14499. (# contributed equally). 

14. Sun, H.; Fang, X.; Chi, Y. R.*; Li, G.* Theoretical Study of N-Heterocyclic Carbenes-Catalyzed Cascade Annulation of Benzodienones and Enals. Chirality 2013, 25, 521-528. 

13. Lee, Y.-J. C.; Wu, B.; Raymond, J. E.; Zeng, Y.; Fang, X.; Wooley, K. L.; Liu, W. R.* A Genetically Encoded Acrylamide Functionality. ACS Chem. Biol. 2013, 8 ,1664-1670. 

12. Chen, X.#; Fang, X.#; Chi, Y. R.* Cis-Enals in N-Heterocyclic Carbene-Catalyzed Reactions: Distinct Stereo-Selectivity and Reactivity. Chem. Sci. 2013, 4, 2613-2618. (# contributed equally)  

11. Wang, Y.-S.#; Fang, X.#; Chen, H.-Y.; Wu, B.; Wang, Z. U.; Hilty, C.; Liu, W. R.* Genetic Incorporation of Twelve meta-Substituted Phenylalanine Derivatives Using a Single Pyrrolysyl-tRNA Synthetase Mutant. ACS Chem. Biol. 2013, 8, 405-415. (# contributed equally) 

10. Wang, Y.-S.; Fang, X.; Wallace, A. L.; Wu, B.; Liu, W. R.* A Rationally Designed Pyrrolysyl-tRNA Synthetase Mutant with a Broad Substrate Spectrum. J. Am. Chem. Soc. 2012, 134, 2950-2953. 

9. Fang, X.; Chen, X.; Lv, H.; Chi, Y. R.* Enantioselective Stetter Reactions of Enals and Modified Chalcones Catalyzed by N-Heterocyclic Carbene. Angew. Chem., Int. Ed. 2011, 50, 11782-11785. 

8. Lv, H.; Mo, J.; Fang, X.; Chi, Y. R.* Formal Diels-Alder Reactions of Chalcones and Formylcyclopropanes Catalyzed by Chiral N-Heterocyclic Carbenes. Org. Lett. 2011, 13, 5366-5369. 

7. Fang, X.; Chen, X.; Chi, Y. R.* Enantioselective Diels-Alder Reactions of Enals and Alkylidene Diketones Catalyzed by N-Heterocyclic Carbenes. Org. Lett. 2011, 13, 4708-4711. 

6. Fang, X.; Jiang, K.; Xing, C.; Hao, L.; Chi, Y. R.* A Highly Regio- and Stereoselective Cascade Annulation of Enals and Benzodi(enone)s Catalyzed by N-Heterocyclic Carbenes. Angew. Chem., Int. Ed. 2011, 50, 1910-1913. 

5. Fang, X.; Liu, K.; Li, C.* Efficient Regio- and Stereoselective Formation of Azocan-2-ones via 8-Endo Cyclization of α-Carbamoyl Radicals. J. Am. Chem. Soc. 2010, 132, 2274-2283. 

4. Fang, X.; Xu, H.-J.; Jiang, H.; Liu, Y.-C.*; Fu, Y.; Wu, Y.-D.* A Study on the Reactions of NADH Models with Electron Deficient Alkenes. A Probe for the Extreme of Concerted Electron-hydrogen Atom Transfer Mechanism. Tetrahedron Lett. 2009, 50, 312-315. 

3. Pan, Y.; Lu, H.; Fang, Y.; Fang, X.; Chen, L.; Qian, J.; Wang, J.; Li, C.* Synthesis of Pyrroles via Copper-Catalyzed Coupling of Amines with Bromoenones. Synthesis 2007, 1242-1246. 

2. Fang, X.; Liu, Y.-C.*; Li, C.* 9-Phenyl-10-methylacridinium: A Highly Efficient and Reusable Organocatalyst for Mild Aromatization of 1,4-Dihydropyridines by Molecular Oxygen. J. Org. Chem. 2007, 72, 8608-8610. 

1. Fang, X.; Liu, Y.-C.*; Wang, G.-W.; Ke, Y.-P. A Novel Coenzyme NADH Model 1-Benzyl-1,4-dihydronicotinamide-mediated Reaction: A Single Intermediate Serves two Mechanisms. Res. Chem. Intermediat. 2006, 32, 603-611. 

 

patent

1. 房新强, 孙德谦, 杨爽, 苯并硼唑类化合物的制备方法, 2022, CN113121578B

2. 房新强, 刘剑, 杨爽, 一种手性a-氟代酮化合物的制备方法, 2022，CN112279765B

3. 房新强, 刘剑, 杨爽, 一种手性a-氘代酮的制备方法, 2022, CN112299996B

4. 房新强, 张浩, 杨爽, 一种联烯醇类化合物的制备方法, 2024, CN116102403B


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