陈卓，研究员，博士生导师。中国科学院海西院相关人才计划入选者、福建省引进高层次创业创新人才相关人才计划创新类获得者、福建省省级高层次人才（B类）。主要从事光化学、光生物学及光动力学疗法的基础和转化研究，探索光动力学疗法的作用机制及以成像介导的光动力学疗法的优化，包括对癌症、病原微生物感染的治疗研究等，并取得了系列重要成果。在Angew. Chem. Int. Ed., Molecular Cancer, Cancer Letters, Nanoscale, Drug Discovery Today, Journal of Medicinal Chemistry, Acta Biomaterialia等国际著名刊物发表学术论文100多篇，其中封面/封底/卷首彩页论文4篇。论文近五年他引3000多次，其中3篇入选近十年化学、材料、物理领域ESI高被引频次（top 1%）论文。合作出版《Imaging in Photodynamic Therapy》（CRC Press）英文专章1篇。申请国内外发明专利19项（已授权16项）。系列研究成果先后被Angew. Chem. Int. Ed. Press Release、Wiley.com Newsroom、Chemistry Views Bulletin、CRE中国稀土网站、纳米人、中科院之声（国内及国际版）等多家媒体进行专栏报道或评述，并先后于2014年、2016年及2019年三次入选年度“中国稀土十大科技新闻”。
目前担任《中国医药导报》、《海峡药学》等期刊编委、中国光学学会生物医学光子学专委会委员、福建省生物工程学会常务理事、福建省药理学会肿瘤药理专业委员会常委、以及中国化学会、中国药学会、中国药理学会、中国光学学会、RSC、Elsevier、Wiley-VCH、Springer等多种SCI国际刊物审稿专家。
曾先后主持并完成6项国家自然科学基金面上项目，目前在研国家重点研发计划、物构所“前瞻跨越”揭榜挂帅项目等，主要涉及新型纳米荧光生物标记材料对重大疾病（如肿瘤）标志物的检测及靶向生物成像、光动力抗肿瘤及抗病原菌等领域。
已发表论文：ORCID: http://orcid.org/0000-0002-6351-8689
联系方式：Email: zchen@fjirsm.ac.cn Tel: (591)-63001016
办公室地点：中国科学院海西研究院 中国科学院福建物质结构研究所
福建省福州市闽侯县高新区高新大道8号嘉锡楼506室
从事领域：分子药理学和治疗学
1) 基于稀土发光纳米探针的重大疾病（肿瘤、心脑血管疾病等）标志物体外检测；
2) 光动力抗耐药菌感染；
3) 肿瘤靶向性治疗。
Prof. Zhuo Chen is a recipient of the “Hundred Talents Program” of the Haixi Institutes of the Chinese Academy of Sciences,an innovation award winner of the “Hundred Talents Program” for attracting high-level entrepreneurs and innovative talents in Fujian Province,and a provincial high-level talent (Class B) in Fujian Province. She is mainly engaged in fundamental and translational research in photochemistry,photobiology,and photodynamic therapy,exploring the mechanism of photodynamic therapy and optimizing imaging-guided photodynamic therapy,including the treatment of cancer and pathogenic microbial infections. She has published more than 100 academic papers in internationally renowned journals such as Angew. Chem. Int. Ed.,Molecular Cancer,Cancer Letters,Nanoscale,Drug Discovery Today,Journal of Medicinal Chemistry and Acta Biomaterialia,including four cover/back cover/front color page papers. Her papers have been cited over 3,000 times in the past five years,and three of them have been selected as ESI highly cited papers (top 1%) in the fields of chemistry,materials,and physics in the past ten years. She has also co-authored a chapter in the English book “Imaging in Photodynamic Therapy” (CRC Press) and has applied for 19 invention patents at home and abroad (16 of them have been authorized). Her research achievements have been profiled and reviewed by multiple media outlets,including Angew. Chem. Int. Ed. Press Release,Wiley.com Newsroom,Chemistry Views Bulletin,CRE China Rare Earth Website,Nanoren and the Voice of the Chinese Academy of Sciences (domestic and international editions). She has been selected as one of the “Top Ten Scientific and Technological News of China’s Rare Earth” for three times in 2014,2016,and 2019.
Currently,she serves as an editorial board member of journals such as China Medical Herald and Strait Pharmaceutical Journal,a member of the Biomedical Photonics Special Committee of the Chinese Optical Society,an executive director of the Fujian Society of Bioengineering,a standing committee member of the Tumor Pharmacology Professional Committee of Fujian Provincial Pharmacological Society,and a reviewer for multiple SCI international journals,including those affiliated with institutions such as the Chinese Chemical Society,Chinese Pharmaceutical Association,Chinese Pharmacological Society,Chinese Optical Society,Royal Society of Chemistry (RSC),Elsevier,Wiley-VCH,and Springer.
She has presided over and completed six National Natural Science Foundation of China general projects. Currently,she is working on several ongoing projects,including the National Key Research and Development Program and the “Forward-looking and Leapfrogging” Challenge Project of the Institute of Structural Biology,which mainly involve the detection and targeted biological imaging of major disease markers (such as tumors) using novel nano-fluorescent biomarker materials,as well as photodynamic anti-tumor and anti-pathogen research.
